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Recruiting NCT06919484
The Physiological Effect of RCexp on Ventilation/Perfusion Distribution
Trial Parameters
Condition Acute Respiratory Distress Syndrome
Sponsor Southeast University, China
Study Type OBSERVATIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 19 Years
Max Age N/A
Start Date 2025-11-30
Completion 2026-12-31
All Conditions
Interventions
RCexp
Brief Summary
With the exception of setting the positive end-expiratory pressure (PEEP), the expiratory phase is commonly overlooked during MV. The expiratory time constant (RCexp) plays an important role in understanding the mechanical properties of the respiratory system in patients receiving mechanical ventilation. However, it is unclear that the effect of expiratory time constant on the ventilation and perfusion distribution.
Eligibility Criteria
Inclusion Criteria: adult patients with ARDS receiving mechanical ventilation no more than 72 hours Exclusion Criteria: 1. age \<18 years old 2. patient undergoing legal protection 3. contra-indications to EIT (e. g. severe chest trauma or wounds) 4. pneumothorax 5. patient undergoing ECMO 6. pregnancy