NCT07543666 The ISAR InflEx Trial (Inflammation and Exercise)
| NCT ID | NCT07543666 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Department of Cardiology German Heart Center Munich TUM University Hospital |
| Condition | Inflammation |
| Study Type | INTERVENTIONAL |
| Enrollment | 33 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 33 participants in total. It began in 2026-01-01 with a primary completion date of 2027-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD). This study aims to systematically characterize and compare the effects of three distinct exercise modalities - moderate-intensity, vigorous-intensity, and short-duration maximal exercise - each differing in duration and intensity, on systemic inflammation and immune function. The study investigates the potential of exercise as an effective anti-inflammatory intervention for the prevention of CVD.
Eligibility Criteria
Inclusion Criteria: * BMI 25.0 - 30.0 kg/m² * age 18 - 45 years * informed consent * no regular physical activity (≤1x/week of structured exercise) * willingness to strictly follow and adhere to the intervention protocol for the entire study Exclusion Criteria: * any acute or chronic illness * pregnancy and breastfeeding * active smoking * Regular use of medication
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07543666 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Inflammation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07543666 currently recruiting?
Yes, NCT07543666 is actively recruiting participants. Contact the research team at hendrik.sager@tum.de for enrollment information.
Where is the NCT07543666 trial being conducted?
This trial is being conducted at München, Germany.
Who is sponsoring the NCT07543666 clinical trial?
NCT07543666 is sponsored by Department of Cardiology German Heart Center Munich TUM University Hospital. The trial plans to enroll 33 participants.