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Recruiting NCT05738603

The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.

Trial Parameters

Condition Hypotension
Sponsor Jakub Szrama
Study Type INTERVENTIONAL
Phase N/A
Enrollment 206
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-09-01
Completion 2026-09-30
Interventions
Hypotension Prediction Index

Brief Summary

The aim of the current study is to evaluate the effects of the Hypotension Prediction Index (HPI) on the degree of intraoperative hypotension in patients undergoing free flap surgery. The hypothesis is that implementation of the HPI algorithm will reduce the time-weighted average (TWA) intraoperative hypotension below a threshold of 65 mmHg (16), and to reveal the relationship between the episodes of hypotension and free flap viability and function.

Eligibility Criteria

Inclusion Criteria: * Patients qualified to head and neck free flap surgery * Written informed consent Exclusion Criteria: * Patients under 18 years * Lack of health insurance * Pregnancy * Known history of congenital heart disease, severe aortic and/or mitral stenosis, heart failure and ejection fraction \< 35 % * Persistent atrial fibrillation and other arrhythmias impairing arterial pressure-based cardiac output (APCO) monitoring

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