| NCT ID | NCT05492708 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Heartland Health Research Alliance |
| Condition | Pregnancy Related |
| Study Type | OBSERVATIONAL |
| Enrollment | 2,600 participants |
| Start Date | 2020-01-11 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 2,600 participants in total. It began in 2020-01-11 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.
Eligibility Criteria
Inclusion Criteria: * Pregnant persons ages 18 or older at time of consent who are ≤20+6 weeks pregnant. Best clinical estimate of gestational age will be utilized for recruitment purposes. Enrollment in the first trimester (≤ 13 + 6) is preferred, but anyone ≤ 20 +6 is permitted. * Living in one of the 13 Heartland Study region states at the time of enrollment (Arkansas, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, or Wisconsin) Optional inclusion of the putative biological father Exclusion Criteria: * Participants who are not fluent in and/or do not fully understand, read, write, or speak the English language. * Other inability to provide informed consent to participate
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05492708 clinical trial?
This trial is open to female participants only, aged 18 Years or older, studying Pregnancy Related. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05492708 currently recruiting?
Yes, NCT05492708 is actively recruiting participants. Contact the research team at kamaflan@iu.edu for enrollment information.
Where is the NCT05492708 trial being conducted?
This trial is being conducted at Indianapolis, United States, Iowa City, United States, La Crosse, United States, Marshfield, United States.
Who is sponsoring the NCT05492708 clinical trial?
NCT05492708 is sponsored by Heartland Health Research Alliance. The trial plans to enroll 2,600 participants.