NCT05912348 The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
| NCT ID | NCT05912348 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of New Hampshire |
| Condition | Insulin Resistance |
| Study Type | INTERVENTIONAL |
| Enrollment | 45 participants |
| Start Date | 2023-02-08 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 45 participants in total. It began in 2023-02-08 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women? 3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?
Eligibility Criteria
Inclusion Criteria: * 18-30 years of age * Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (\>2 days/week). * Fair cardiorespiratory fitness levels (Men: VO2\>38.4 ml/kg/min; Women: VO2\>32.6 ml/kg/min). Exclusion Criteria: * Hypertension (resting or diagnosed) * Impaired fasting blood glucose (\>100mg/dL) * Diagnosed cardiovascular disease * Diagnosed diabetes * Diagnosed cancer * Diagnosed chronic kidney disease * Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.
Contact & Investigator
Michael S Brian, PhD
PRINCIPAL INVESTIGATOR
University of New Hampshire
Frequently Asked Questions
Who can join the NCT05912348 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Insulin Resistance. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05912348 currently recruiting?
Yes, NCT05912348 is actively recruiting participants. Contact the research team at Michael.Brian@unh.edu for enrollment information.
Where is the NCT05912348 trial being conducted?
This trial is being conducted at Durham, United States.
Who is sponsoring the NCT05912348 clinical trial?
NCT05912348 is sponsored by University of New Hampshire. The principal investigator is Michael S Brian, PhD at University of New Hampshire. The trial plans to enroll 45 participants.