NCT06522087 The Effect of 40 Hz Transcranial Stimulation on the Incidence of Delirium After Total Hip Replacement or Total Knee Replacement Arthroplasty in Elderly Patients.
| NCT ID | NCT06522087 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Henan Provincial People's Hospital |
| Condition | Postoperative Delirium |
| Study Type | INTERVENTIONAL |
| Enrollment | 110 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2025-03-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 110 participants in total. It began in 2024-05-01 with a primary completion date of 2025-03-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Delirium is an acute confusional state, it is a sign of acute encephalopathy, also known as acute brain failure, acute brain dysfunction or mental state changes.Postoperative delirium can cause post-traumatic stress disorder, affects patients' quality of life, extend the length of hospital stay, increased hospitalization cost, and is closely relative to short-term and long-term mortality after surgery. Exogenous 40 Hz stimulation can improve cognitive functioning. Therefore, the aim of this study was to investigate the effect of exogenous 40Hz stimulation on the incidence of postoperative delirium in elderly patients undergoing hip and knee replacement.
Eligibility Criteria
Inclusion Criteria: 1.65-85 years old, gender not limited 2.General anesthesia unilateral total hip replacement surgery or unilateral total knee replacement 3.ASA classification I-III 4.No drugs for mental and central nervous system diseases were used before surgery 5.Preoperative MMSE score illiterate \> 17 points, primary \> 20 points, junior high school and above \> 24 points 6.Obtaining informed consent Exclusion Criteria: 1. Severe liver and kidney dysfunction 2. here were mental and nervous system diseases before operation 3. Have a history of alcoholism, long-term use of sedative or analgesic 4. A history of a delirium and other reasons are reluctant to cooperate 5. Massive blood loss and blood transfusion during operation, prolonged operation time
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06522087 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, up to 85 Years, studying Postoperative Delirium. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06522087 currently recruiting?
Yes, NCT06522087 is actively recruiting participants. Contact the research team at hnmzxh@163.com for enrollment information.
Where is the NCT06522087 trial being conducted?
This trial is being conducted at Zhengzhou, China.
Who is sponsoring the NCT06522087 clinical trial?
NCT06522087 is sponsored by Henan Provincial People's Hospital. The trial plans to enroll 110 participants.