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Recruiting NCT03720522
The Bern Heart and Brain Interaction Study - Interaction Between Brain and Heart in Acute Ischemic Stroke
Trial Parameters
Condition Acute Stroke
Sponsor Insel Gruppe AG, University Hospital Bern
Study Type OBSERVATIONAL
Phase N/A
Enrollment 220
Sex ALL
Min Age 18 Years
Max Age 86 Years
Start Date 2018-12-01
Completion 2025-12-31
Interventions
Short cardiovascular MRI (CMR)Adenosine-perfusion cardiovascular MRI (CMR)Blood draw
Brief Summary
Acute ischemic stroke is caused by blockage of blood vessels in the brain. Blood vessels can be obstructed by several different mechanisms and identification of this cause is essential to minimize the risk of recurrence.
Eligibility Criteria
Inclusion Criteria: * Informed consent as documented by signature. * Age: ≥ 18 and \< 86 years. * Acute ischemic stroke with symptom onset within 12 hours before admission to hospital. * Diagnosis of acute ischemic stroke with MRI with diffusion restriction as seen on diffusion weighted imaging. Exclusion Criteria: * Pregnancy. A negative pregnancy test upon admission is required for all women with child-bearing potential. * Standard contraindication for performing MRI. * Severe renal failure (GFR \<40).
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