← Back to Clinical Trials
Recruiting NCT05234177

NCT05234177 Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05234177
Status Recruiting
Phase
Sponsor Tempus AI
Condition Colorectal Cancer
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2022-06-21
Primary Completion 2027-02

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Observation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2022-06-21 with a primary completion date of 2027-02.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.

Eligibility Criteria

Inclusion Criteria: * Known or suspected colorectal adenocarcinoma (Stage I to IVA disease) * Planning to undergo or has undergone a surgical resection for suspected adenocarcinoma of the colon or rectum with curative intent. * 18 years old or older * Willing and able to provide informed consent * Willing to have additional blood samples collected during routine surveillance visits Exclusion Criteria: * Not willing to have additional blood samples collected * Pathology that is not consistent with colorectal adenocarcinoma

Contact & Investigator

Central Contact

CRC Surveillance Study

✉ gemini-crc@tempus.com

📞 (833) 514-4187

Principal Investigator

Kristiyana Kaneva, MD, MS

PRINCIPAL INVESTIGATOR

Tempus AI, Inc.

Frequently Asked Questions

Who can join the NCT05234177 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05234177 currently recruiting?

Yes, NCT05234177 is actively recruiting participants. Contact the research team at gemini-crc@tempus.com for enrollment information.

Where is the NCT05234177 trial being conducted?

This trial is being conducted at Fort Smith, United States, Fountain Valley, United States, Bethesda, United States, Joplin, United States and 11 additional locations.

Who is sponsoring the NCT05234177 clinical trial?

NCT05234177 is sponsored by Tempus AI. The principal investigator is Kristiyana Kaneva, MD, MS at Tempus AI, Inc.. The trial plans to enroll 300 participants.

Related Trials

Related Intelligence Guides

In-depth guides covering this condition's trials, eligibility, and what to expect.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology