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Recruiting NCT05439863

TAVR for Aortic Valve Disease

Trial Parameters

Condition Aortic Valve Disease
Sponsor Nanjing First Hospital, Nanjing Medical University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 5,000
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-07-01
Completion 2032-12-30
Interventions
transcatheter heart valve

Brief Summary

Transcatheter aortic valve replacement (TAVR) has became an important treatment of severe aortic stenosis (AS). Several randomized clinical trials showed that TAVR was non-inferior or superior to surgical aortic valve replacement (SAVR). However, many different issues have emerged: TAVR in younger patients? valve leaflet thrombosis? transcatheter valve durability? coronary reaccess after TAVR? TAVR in bicuspid aortic valve? TAVR in aortic regurgitation? etc. Hence, a prospective, multicenter database is created to provide the real-word data for these questions.

Eligibility Criteria

Inclusion Criteria: 1. Clinical diagnosis of severe aortic stenosis or aortic regurgitation 2. Patients undergo transcatheter aortic valve replacement Exclusion Criteria: patients refuse the clinical follow-up

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