NCT05847270 Surgical Treatment of Irreducible Atlantoaxial Dislocation
| NCT ID | NCT05847270 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Peking University Third Hospital |
| Condition | Irreducible Atlantoaxial Dislocation |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2023-07-11 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2023-07-11 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
At present, there is a lack of standardized, large-scale, and high-level evidence-based medicine research on the safety and effectiveness of treatment of irreducible atlantoaxial dislocation (IAAD).Based on this, the goal of this prospective randomized controlled study is to systematically investigate the optimal surgical approach (simple posterior approach and the combined anterior and posterior approach) for managing IAAD, providing insights into the most efficacious and safest course of action. And long-term follow-up will be conducted on patients to evaluate the safety and effectiveness of different surgical methods, and to develop diagnostic and treatment standards for irreducible atlantoaxial dislocation.
Eligibility Criteria
Inclusion Criteria: 1. Eligible participants encompass individuals within the age range of 0 to 80 years, without regard to gender. 2. Patients who have received a diagnosis of irreducible atlantoaxial dislocation (IAAD) based on preoperative imaging and skull traction evaluation, with a traction weight equivalent to 1/6 of their body weight following anesthesia. These patients are candidates for surgical intervention. 3. Participants who have provided informed consent either in person or through their legal representative (the principal). Exclusion Criteria: 1. Individuals with concomitant medical conditions or diseases that significantly impact surgical treatment, such as malignant metastasis or infectious diseases, will be excluded from the study. 2. Critically ill patients, who are not suitable candidates for surgical intervention, will also be excluded. 3. Patients who actively decline to participate in this research project will not be included in the study cohort.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05847270 clinical trial?
This trial is open to participants of all sexes, up to 80 Years, studying Irreducible Atlantoaxial Dislocation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05847270 currently recruiting?
Yes, NCT05847270 is actively recruiting participants. Contact the research team at pkuwsl@126.com for enrollment information.
Where is the NCT05847270 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT05847270 clinical trial?
NCT05847270 is sponsored by Peking University Third Hospital. The trial plans to enroll 70 participants.