NCT07419438 Supraglottic Airway for Resuscitation in Preemies
| NCT ID | NCT07419438 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pennsylvania |
| Condition | Respiratory Failure |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2026-03-13 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2026-03-13 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation (PPV) is feasible during delivery room resuscitation of premature infants. This study will be conducted in premature infants born between 29 0/7 and 33 6/7 weeks' gestation who require PPV at birth. The main question it aims to answer is: Is it feasible to use a supraglottic airway as the primary interface to provide effective PPV during delivery room resuscitation in 29 0/7 to 33 6/7 weeks' gestation premature infants? Participants will (1)Be screened prenatally and have informed consent obtained from the birth parent prior to delivery; (2)Be rescreened for eligibility on the day of delivery before receiving the study intervention; (3)Receive PPV using a supraglottic airway as the primary ventilation interface if resuscitation is required at birth; and (4)Have clinical and procedural data collected during delivery room resuscitation and for up to 24 hours after birth.
Eligibility Criteria
Inclusion Criteria: * Gestational age 29 0/7 to 33 6/7 weeks at birth * Estimated fetal weight \>/= 1000 grams at birth * Clinical decision to initiate PPV * Parental informed consent Exclusion Criteria: * Major anomalies or aneuploidy * Palliative care planned or considered * Not resuscitated in the infant resuscitation room
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07419438 clinical trial?
This trial is open to participants of all sexes, aged 0 Days or older, up to 1 Day, studying Respiratory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07419438 currently recruiting?
Yes, NCT07419438 is actively recruiting participants. Contact the research team at sura.lee@pennmedicine.upenn.edu for enrollment information.
Where is the NCT07419438 trial being conducted?
This trial is being conducted at Philadelphia, United States.
Who is sponsoring the NCT07419438 clinical trial?
NCT07419438 is sponsored by University of Pennsylvania. The trial plans to enroll 20 participants.