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Recruiting NCT07160296

Supporting Treatment Resilience With Optimized Nutrition and Guided Exercise in Head and Neck Cancer Patients Undergoing Chemoradiation

Trial Parameters

Condition Head and Neck Cancer
Sponsor Renown Health
Study Type INTERVENTIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-09-15
Completion 2026-09-30
Interventions
20-Week Lifestyle Program

Brief Summary

The purpose of this study to find out whether a structured lifestyle intervention-combining nutrition counseling, guided exercise, and wellness education-can help reduce treatment-related side effects and improve physical function, resilience, and quality of life in patients with head and neck cancer undergoing chemoradiation therapy (chemoRT). Benefits of research cannot be guaranteed but we hope to learn whether this intervention is feasible and acceptable during active cancer treatment, and whether it can help preserve lean body mass, improve strength and endurance, and support emotional well-being. The findings will inform the design of a future larger clinical trial.

Eligibility Criteria

Inclusion Criteria: * Adults ≥18 years old with biopsy-confirmed squamous cell carcinoma of the head and neck * Planned for definitive or adjuvant chemoRT * ECOG performance status 0-2 * Ability to participate in light-to-moderate physical activity * Able to provide informed consent Exclusion Criteria: * Severe malnutrition requiring exclusive enteral feeding at baseline * Comorbidities that preclude safe participation in exercise * Cognitive or psychiatric conditions that impair study engagement

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