NCT07245979 Supplementation With Sirtuin Activators in Women With Increased Body Weight
| NCT ID | NCT07245979 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Poznan University of Life Sciences |
| Condition | Obesity & Overweight |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2025-10-08 |
| Primary Completion | 2026-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2025-10-08 with a primary completion date of 2026-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.
Eligibility Criteria
Inclusion Criteria: * females * age: 40-65 years * overweight or obese: BMI \>25 kg/m2 Exclusion Criteria: * males * BMI \< 25 kg/m2 * sirtuin activators administration for 3 months prior to study * pregnancy or breastfeeding * recent dieting or being on calorie restricted diet * receiving pharmacotherapy to treat obesity, diabetes or hyperlipidemia * post-bariatric surgery * diabetes * cancer * chronic kidney, liver or autoimmune diseases * alcohol addiction
Contact & Investigator
Agata Chmurzynska, Professor
PRINCIPAL INVESTIGATOR
Poznan Univeristy of Life Sciences
Frequently Asked Questions
Who can join the NCT07245979 clinical trial?
This trial is open to female participants only, aged 40 Years or older, up to 65 Years, studying Obesity & Overweight. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07245979 currently recruiting?
Yes, NCT07245979 is actively recruiting participants. Contact the research team at agata.chmurzynska@up.poznan.pl for enrollment information.
Where is the NCT07245979 trial being conducted?
This trial is being conducted at Poznan, Poland.
Who is sponsoring the NCT07245979 clinical trial?
NCT07245979 is sponsored by Poznan University of Life Sciences. The principal investigator is Agata Chmurzynska, Professor at Poznan Univeristy of Life Sciences. The trial plans to enroll 120 participants.
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