NCT07251244 Supplement and Exercise Effects on Stationary Immunity and Health in Older Adults
| NCT ID | NCT07251244 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Valencia |
| Condition | Aging |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-12-15 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2025-12-15 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn whether a natural-origin nutritional supplement, combined with a moderate-intensity functional exercise program, can improve seasonal immunity, perceived health, and oxidative stress in older adults. The study will also assess the safety of this combined intervention. The main questions it aims to answer are: * Does the combination of supplementation and exercise enhance immune function during seasonal changes? * Does it reduce oxidative stress and improve perceived health and functional capacity? Researchers will compare a supplement to a placebo. All participants will follow the same supervised functional exercise program. Participants will: * Take a daily nutritional supplement for 6 months. * Attend two weekly functional exercise sessions (60 minutes each), including mobility, explosive strength, and coordination/agility training. * Complete three assessments (before, midway, and after the intervention) including blood tests, physical function evaluations, and quality of life questionnaires.
Eligibility Criteria
Inclusion Criteria: * Adults aged 65 years or older * Functional independence, defined as the ability to perform activities of daily living without assistance * Sufficient cognitive capacity to understand instructions and complete questionnaires, assessed through interview or brief cognitive screening if necessary * Not immunosuppressed * Not regular users of antioxidant or immunomodulatory supplements * Ability and availability to attend exercise sessions and scheduled assessments throughout the six-month study period * Commitment to maintain stable dietary and physical activity habits during the intervention Exclusion Criteria: * Active autoimmune diseases or clinically relevant immunosuppression * Use of corticosteroids or immunosuppressive drugs in the 4 weeks prior to study initiation * Active infection or compatible symptoms (fever, cough, diarrhea) in the 2 weeks prior to any measurement * Unstable cardiovascular conditions or medical contraindications for moderate physical exercise * Moderate to severe cognitive impairment that prevents proper participation in the scheduled activities * Participation in another clinical trial in the last 3 months * Known allergy or hypersensitivity to the supplement or any of its excipients
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07251244 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Aging. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07251244 currently recruiting?
Yes, NCT07251244 is actively recruiting participants. Contact the research team at juan.colado@uv.es for enrollment information.
Where is the NCT07251244 trial being conducted?
This trial is being conducted at Valencia, Spain.
Who is sponsoring the NCT07251244 clinical trial?
NCT07251244 is sponsored by University of Valencia. The trial plans to enroll 60 participants.