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Recruiting NCT06633978

NCT06633978 Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

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Clinical Trial Summary
NCT ID NCT06633978
Status Recruiting
Phase
Sponsor University of California, San Francisco
Condition MCI
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2024-09-10
Primary Completion 2026-08

Eligibility & Interventions

Sex All sexes
Min Age 60 Years
Max Age 85 Years
Study Type INTERVENTIONAL
All Conditions
Interventions
MediTrainwrist worn multi-sensor watchesSleep monitor

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 90 participants in total. It began in 2024-09-10 with a primary completion date of 2026-08.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this proposed research is to collect pilot data to test the hypothesis that treatment with a novel form of closed-loop digital meditation (MediTrain) will lead to a greater magnitude of gains in cognitive abilities in patients with mild cognitive impairment (MCI), compared to OA without cognitive impairment, and will lead to improvements in quantitative measures of sleep.

Eligibility Criteria

* comfortably ambulatory healthy physical condition * normal or corrected to normal visual * auditory acuity * fluency in spoken English * Between 60-85 years old * No neurological or psychiatric disorders * No substance abuse * Not taking anti-depressants * Not taking anti-anxiety medication * No history of seizures * No color blindness * No glaucoma * No macular degeneration * No amblyopia (lazy eye) * No strabismus (cross eyed) * Aneurysm clip(s) * No Cardiac pacemaker * No Implanted cardioverter defibrillator (ICD) * No Electronic implant or device * No Magnetically-activated implant or device * No Neurostimulation system * No Spinal cord stimulator * No Internal electrodes or wires * No Bone growth/bone fusion stimulator * No Cochlear, otologic, or other ear implant * No Insulin or other infusion pump * No Implanted drug infusion device * No type of prosthesis (eye, penile, etc.) * No Heart valve prosthesis * No Eyelid spring or wire * No Artificial or prosthetic limb * No Metallic stent, filter, or coil * No Shunt (spinal or intraventricular) * No Vascular access port and/or catheter * No Radiation seeds or implants * No Swan-Ganz or thermodilution catheter * No Medication patch (Nicotine, Nitroglycerine) * No metallic fragment or metallic foreign body in/on the body that can not be removed * No Wire mesh implant * No Tissue expander (e.g., breast) * No Surgical staples, clips, or metallic sutures * No Joint replacement (hip, knee, etc.) * No Bone/joint pin, screw, nail, wire, plate, etc. * No IUD, diaphragm, or pessary * No Dentures or partial plates that can not be removed * No Tattoo or permanent makeup * No Body piercing jewelry * No Claustrophobia

Contact & Investigator

Central Contact

Joseph Chen, PhD

✉ medidream@ucsf.edu

📞 415-476-2164

Principal Investigator

David A Ziegler, PhD

PRINCIPAL INVESTIGATOR

University of California, San Francisco

Frequently Asked Questions

Who can join the NCT06633978 clinical trial?

This trial is open to participants of all sexes, aged 60 Years or older, up to 85 Years, studying MCI. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06633978 currently recruiting?

Yes, NCT06633978 is actively recruiting participants. Contact the research team at medidream@ucsf.edu for enrollment information.

Where is the NCT06633978 trial being conducted?

This trial is being conducted at San Francisco, United States.

Who is sponsoring the NCT06633978 clinical trial?

NCT06633978 is sponsored by University of California, San Francisco. The principal investigator is David A Ziegler, PhD at University of California, San Francisco. The trial plans to enroll 90 participants.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology