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Recruiting NCT06547099

NCT06547099 Study to Understand Novel Biomarkers in Researching Dementia

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Clinical Trial Summary
NCT ID NCT06547099
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Alzheimer Disease
Study Type OBSERVATIONAL
Enrollment 1,800 participants
Start Date 2024-08-14
Primary Completion 2028-12

Eligibility & Interventions

Sex All sexes
Min Age 60 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Clinical tau PETClinical amyloid testResearch blood collection

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,800 participants in total. It began in 2024-08-14 with a primary completion date of 2028-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's disease (AD) pathology, clinical cognitive decline, and diagnosis. We aim to understand how well blood-based biomarkers can diagnose and predict Alzheimer's disease, which will help to further develop and validate blood tests for the disease.

Eligibility Criteria

Inclusion Criteria: * At least 60 years of age * 80% of the newly enrolled clinic-based cohort will have symptoms of forgetfulness, mild cognitive impairment, mild dementia, or Alzheimer's disease as determined by their medical chart and/or provider * All SEABIRD participants will be invited to participate regardless of their cognitive status Exclusion Criteria: * Unable to perform one or more basic activities of daily living (eating, bathing, dressing, ambulating, toileting) due to cognitive impairment * Uncontrolled hepatitis B, hepatitis C, or HIV at time of blood collection * Taking a disease-modifying drug for AD at time of enrollment * Blood transfusion in the last three months * Unwilling or unable to participate in all study activities

Contact & Investigator

Central Contact

Lisa Soke

✉ sunbirdstudy@wustl.edu

📞 314-747-4857

Principal Investigator

Randall Bateman, MD

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT06547099 clinical trial?

This trial is open to participants of all sexes, aged 60 Years or older, studying Alzheimer Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06547099 currently recruiting?

Yes, NCT06547099 is actively recruiting participants. Contact the research team at sunbirdstudy@wustl.edu for enrollment information.

Where is the NCT06547099 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT06547099 clinical trial?

NCT06547099 is sponsored by Washington University School of Medicine. The principal investigator is Randall Bateman, MD at Washington University School of Medicine. The trial plans to enroll 1,800 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology