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Recruiting NCT06817434

Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease

Trial Parameters

Condition Moyamoya Disease
Sponsor Beijing Tiantan Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 330
Sex ALL
Min Age 18 Years
Max Age 60 Years
Start Date 2024-12-15
Completion 2025-12-31
Interventions
Revascularization/Conservative management

Brief Summary

The purpose of this study is to investigate the effectiveness of statins in the treatment of moyamoya disease based on multimodal magnetic resonance imaging.

Eligibility Criteria

Inclusion Criteria: 1. The imaging examination meets the diagnostic criteria for moyamoya disease; 2. Sign the informed consent form; 3. Age ≥18 years old; 4. Baseline mRS score ≤2 points; 5. The patient receives revascularization/conservative treatment; 6. There is at least 1 imaging follow-up result. Exclusion Criteria: 1. Patients with atherosclerosis, autoimmune diseases, meningitis, Down syndrome, cranial trauma, or those who have undergone radioactive head irradiation, as these conditions may lead to secondary cerebrovascular disease and contribute to the development of Moyamoya syndrome; 2. Individuals under the age of 18; 3. Participants who refuse to take part in this study; 4. Pregnant patients; 5. Those with concurrent intracranial aneurysms, cerebrovascular malformations, brain tumors, or hydrocephalus; 6. A history of stroke occurring more than three months prior to the diagnosis of Moyamoya disease; 7. Individuals with a history of coronary heart disease or previous cardi

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