Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation
Trial Parameters
Brief Summary
To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial functional mitral regurgitation.
Eligibility Criteria
Inclusion Criteria: 1. Patients aged 18 to 80 years old; 2. Patients diagnosed with symptomatic paroxysmal atrial fibrillation (AF history \< 5 years) 3. Moderate to severe MR and normal LV ejection fraction (≥50%), LVEDD\<55 mm, and normal LV wall systolic function 4. Able to understand the purpose of the trial, participate in the trial voluntarily with informed consent form signed by the subject him/herself or his or her legal representative, and willing to complete follow-up visits as required under the protocol Exclusion Criteria: 1. Atrial fibrillation secondary to electrolyte imbalances, thyroid disease or other reversible factors 2. Active endocarditis or active rheumatic heart disease, or degenerative mitral regurgitation due to endocarditis or rheumatic valvular heart disease 3. Moderate to severe mitral stenosis 4. Imaging examination shows left atrium or left atrial appendage thrombosis 5. Left ventricular ejection fraction less than 50% 6. Left atrial diameter