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Recruiting NCT06891235

NCT06891235 Study of an Oral Fluid Testing Approach

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Clinical Trial Summary
NCT ID NCT06891235
Status Recruiting
Phase
Sponsor Boston Children's Hospital
Condition Cannabis Use
Study Type OBSERVATIONAL
Enrollment 200 participants
Start Date 2025-10-27
Primary Completion 2027-02

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 30 Years
Study Type OBSERVATIONAL
Interventions
Biologic testing for THC

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 200 participants in total. It began in 2025-10-27 with a primary completion date of 2027-02.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-30 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits across \~3-4 weeks and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (\~Day 7; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (\~Day 21; TLFB interview, urine test, oral fluid test, survey, interview).

Eligibility Criteria

Inclusion Criteria: * Age 18 to 30 years * Cannabis use on \>=1x/week in the past 30 days * Ownership of a portable device that is capable of videoconference and videorecording (i.e., smartphone, tablet computer, or laptop computer) * Ability to read and speak English * Availability for duration of the study (3-4 weeks). * To proceed to oral fluid testing, positive result for urinary TCH-COOH Exclusion Criteria: • Inability/unwillingness to provide contact information

Contact & Investigator

Central Contact

Lydia A Shrier, MD, MPH

✉ lydia.shrier@childrens.harvard.edu

📞 (617) 355-8306

Frequently Asked Questions

Who can join the NCT06891235 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Cannabis Use. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06891235 currently recruiting?

Yes, NCT06891235 is actively recruiting participants. Contact the research team at lydia.shrier@childrens.harvard.edu for enrollment information.

Where is the NCT06891235 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT06891235 clinical trial?

NCT06891235 is sponsored by Boston Children's Hospital. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology