NCT07725887 Structured Inpatient Physiotherapy in High-Risk Coronary Artery Bypass Grafting Patients
| NCT ID | NCT07725887 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bezmialem Vakif University |
| Condition | CABG |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-07-22 |
| Primary Completion | 2027-01-02 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-07-22 with a primary completion date of 2027-01-02.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Coronary artery bypass grafting (CABG) may be associated with prolonged recovery, particularly in high-risk patients. Although preoperative rehabilitation has shown promising results, evidence remains limited because of heterogeneous intervention protocols and variations in postoperative care. This study aims to investigate the effects of a structured inpatient physiotherapy program initiated at least two days before surgery and continued postoperatively, compared with the same structured physiotherapy program provided only during the postoperative period, in high-risk CABG patients. The primary outcome is hospital length of stay. Secondary outcomes include intensive care unit length of stay, C-reactive protein, neutrophil-to-lymphocyte ratio, hemoglobin, dyspnea, and fatigue.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older. * Scheduled to undergo elective coronary artery bypass grafting (CABG). * High-risk patients meeting at least three of the following criteria: Left ventricular ejection fraction (LVEF) \<40%. Three-vessel coronary artery disease. More than two comorbidities. History of smoking. Age \>65 years. \- Able and willing to provide written informed consent. Exclusion Criteria: * Planned redo CABG surgery. * Severe neurological or orthopedic conditions limiting mobilization. * Severe cognitive impairment. * Hemodynamic instability. * Contraindications to mobilization or exercise. * Inability to complete at least two days of the preoperative physiotherapy program.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07725887 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying CABG. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07725887 currently recruiting?
Yes, NCT07725887 is actively recruiting participants. Contact the research team at fuat.gokdemir@bezmialem.edu.tr for enrollment information.
Where is the NCT07725887 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07725887 clinical trial?
NCT07725887 is sponsored by Bezmialem Vakif University. The trial plans to enroll 100 participants.