NCT06489470 Strokectomy in Malignant Cerebral Media Infarction
| NCT ID | NCT06489470 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Rostock |
| Condition | Stroke, Ischemic |
| Study Type | INTERVENTIONAL |
| Enrollment | 10 participants |
| Start Date | 2024-06-15 |
| Primary Completion | 2025-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 10 participants in total. It began in 2024-06-15 with a primary completion date of 2025-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Decompressive hemicraniectomy (DC) is the standard procedure and life saving measure in case of malignant middle cerebral artery (MCA) infarction. However, there have been several studies reporting the neuroinflammatory cascade based on the necrotic tissue as one of the leading cause for the secondary brain damage, wherefore, strokectomy with resection of necrotic tissue has been proposed in some case series as an alternative surgical option. Thus, the aim of this study is to perform a pilot study by including patients with malignant MCA infarction and to check the feasibility of this specific surgical treatment.
Eligibility Criteria
Inclusion Criteria: * 18 years of age or older * Ischemic middle cerebral artery (MCA) infarction at least two thirds of the MCA territory * Clinical symptoms of acute unilateral MCA infarction less than 48 hours prior to the initiation of treatment Exclusion Criteria: * Preexisting modified Rankin Scale \>2 * Absence of pupillary reflexes or GCS \<6 * Intracerebral hemorrhage or other associated brain lesions * Contraindications for surgery * Estimated life expectancy of less than 3 years
Contact & Investigator
Sae-Yeon Won, MD
PRINCIPAL INVESTIGATOR
Neurosurgery, University Medical Center Rostock
Frequently Asked Questions
Who can join the NCT06489470 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Stroke, Ischemic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06489470 currently recruiting?
Yes, NCT06489470 is actively recruiting participants. Contact the research team at melanie.sparre@med.uni-rostock.de for enrollment information.
Where is the NCT06489470 trial being conducted?
This trial is being conducted at Rostock, Germany.
Who is sponsoring the NCT06489470 clinical trial?
NCT06489470 is sponsored by University of Rostock. The principal investigator is Sae-Yeon Won, MD at Neurosurgery, University Medical Center Rostock. The trial plans to enroll 10 participants.
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