NCT07345481 Stimulus Equivalence Learning in Acquired Brain Injury.
| NCT ID | NCT07345481 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Klimmendaal Revalidatiespecialisten |
| Condition | Acquired Brain Injury (Including Stroke) |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-01-29 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2026-01-29 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Stimulus Equivalence Learning (SEL) is a form of learning in which stimuli (such as words, pictures, or sounds) become linked to one another in memory, even though this specific connection has not been directly taught. In a typical SEL task, two relations are taught explicitly (A→B and A→C), and the untrained relation (B→C) is then tested. This indirect relation is not intentionally or consciously learned and is considered a form of implicit learning. The principle of stimulus equivalence learning is still rarely applied in cognitive rehabilitation after acquired brain injury (ABI), with the exception of a few small (N=1) treatment studies that have shown positive effects. However, it remains unclear to what extent ABI may affect the ability to acquire stimulus equivalence.
Eligibility Criteria
Inclusion Criteria: ABI patients (\>3 months post-injury), including stroke, traumatic brain injury, brain tumor, encephalitis, and out-of-hospital cardiac arrest (OHCA). Exclusion Criteria: Neurodegenerative disorders Severe psychiatric disorders (including suicidality) Insufficient command of the Dutch language Severe cognitive impairments, aphasia, or visual or hearing problems that make test administration impossible An additional exclusion criterion for controls was any medical condition that could lead to cognitive impairment beyond normal aging, including stroke, TBI, brain tumor, or other forms of brain injury.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07345481 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Acquired Brain Injury (Including Stroke). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07345481 currently recruiting?
Yes, NCT07345481 is actively recruiting participants. Contact the research team at e.grevers@klimmendaal.nl for enrollment information.
Where is the NCT07345481 trial being conducted?
This trial is being conducted at Arnhem, Netherlands.
Who is sponsoring the NCT07345481 clinical trial?
NCT07345481 is sponsored by Klimmendaal Revalidatiespecialisten. The trial plans to enroll 40 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.