| NCT ID | NCT07464093 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Brigham and Women's Hospital |
| Condition | Ehlers-Danlos Syndrome (EDS) |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-07 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-07 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.
Eligibility Criteria
Inclusion Criteria: * ≥ 18 years old; * Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD; * Self-reported persistent pain ≥ 3 months; * A minimum of 3/10 self-reported pain intensity in the past week * Able to get on and off the floor without assistance; * Able to communicate fluently in English; and * Able to provide written, informed consent Exclusion Criteria: * Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months; * Recent surgery or acute bone, joint or nerve injury (\<6 months); * Have a history of a severe or progressive neurological or movement disorder; * Pregnant, planning to become pregnant during the study, or currently breast feeding; * Unable to get on and off the floor without assistance; * Unable to complete study procedures due to cognitive impairment; * Unable to provide written, informed consent; or * Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.
Contact & Investigator
Samantha Meints, PhD
PRINCIPAL INVESTIGATOR
Brigham and Women's Hospital
Frequently Asked Questions
Who can join the NCT07464093 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Ehlers-Danlos Syndrome (EDS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07464093 currently recruiting?
Yes, NCT07464093 is actively recruiting participants. Contact the research team at svoss2@bwh.harvard.edu for enrollment information.
Where is the NCT07464093 trial being conducted?
This trial is being conducted at Chestnut Hill, United States.
Who is sponsoring the NCT07464093 clinical trial?
NCT07464093 is sponsored by Brigham and Women's Hospital. The principal investigator is Samantha Meints, PhD at Brigham and Women's Hospital. The trial plans to enroll 100 participants.