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Recruiting NCT04819737

NCT04819737 Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences

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Clinical Trial Summary
NCT ID NCT04819737
Status Recruiting
Phase
Sponsor University Hospital, Basel, Switzerland
Condition Multiple Sclerosis (MS)
Study Type INTERVENTIONAL
Enrollment 10 participants
Start Date 2022-07-18
Primary Completion 2027-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
SC MRIpatient questionnaire

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 10 participants in total. It began in 2022-07-18 with a primary completion date of 2027-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of multiple sclerosis according to established international criteria * Steroid free period: \> 4 weeks * Participation in the Swiss MS Cohort (SMSC) study Exclusion Criteria: * . History of severe (other) neurological, internal or psychiatric disease with SC affection * MRI-related exclusion criteria (questionnaire): 1. Paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the SC) 2. Pacemaker 3. Claustrophobia 4. Pregnancy, lactation 5. Known hypersensitivity to gadolinium-based contrast media

Contact & Investigator

Central Contact

Katrin Parmar, PD Dr. med.

✉ katrin.parmar@unibas.ch

📞 +41 61 83 65 214

Principal Investigator

Katrin Parmar, PD Dr. med.

PRINCIPAL INVESTIGATOR

University Hospital Basel, Department of Neurology

Frequently Asked Questions

Who can join the NCT04819737 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Multiple Sclerosis (MS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04819737 currently recruiting?

Yes, NCT04819737 is actively recruiting participants. Contact the research team at katrin.parmar@unibas.ch for enrollment information.

Where is the NCT04819737 trial being conducted?

This trial is being conducted at Basel, Switzerland.

Who is sponsoring the NCT04819737 clinical trial?

NCT04819737 is sponsored by University Hospital, Basel, Switzerland. The principal investigator is Katrin Parmar, PD Dr. med. at University Hospital Basel, Department of Neurology. The trial plans to enroll 10 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology