Trial Parameters
Brief Summary
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.
Eligibility Criteria
Inclusion Criteria: * Age 18 and up * English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks * Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks * Current nicotine dependent smoker with a minimum smoking history of 2 years * Interest in quitting smoking Exclusion Criteria: * Use of psychotropic (e.g. antiepileptic) medications in the past month * Positive urine drug screen * Presence of an untreated medical illness * Current or past psychosis * History of major neurological illness or head injury resulting in loss of consciousness * And contraindication to MRI, including claustrophobia * Among females, positive urine pregnancy test * Inability or unwillingness of subject to give informed consent