NCT06423118 Sleep Apnea and Cognition in Older Adults
| NCT ID | NCT06423118 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sunnybrook Health Sciences Centre |
| Condition | Sleep |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2024-04-09 |
| Primary Completion | 2034-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2024-04-09 with a primary completion date of 2034-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this cross-sectional, observational, medical device trial is to examine the association of several sleep parameters, including specific respiratory events and an apnea-hypopnea index, with cognitive performance in older adults. The main question the study aims to answer is: Is there an association between sleep parameters with cognitive performance? Researchers will collect sleep parameters from participants using a device called the ANNE Vital Sign System and will test whether they are associated with performance on different memory and thinking tasks. Participants will: Complete a battery of cognitive tests to assess their memory and thinking performance. Wear the ANNE Vital Sign System continuously for a period of 24 hours.
Eligibility Criteria
Inclusion Criteria: 1. Sufficient knowledge of English to understand and provide informed consent 2. Competent to provide consent 3. Aged 55-85, Male and Female 4. ≥ 8 years of education 5. Capable of cooperating for the duration of the study procedures and assessments 6. No frank cognitive impairment or dementia 7. Sufficient (corrected) vision to participate in cognitive testing 8. Sufficient (corrected) hearing to participate in cognitive testing Exclusion Criteria: 1. Cannot read and comprehend English language instructions 2. Major cardio- or cerebro-vascular event (heart attack, stroke, significant white matter changes) 3. Unstable diseases (e.g., pulmonary, endocrine disorder) 4. Active malignancy or infectious diseases 5. History of significant learning disability 6. Major psychiatric/neurologic/degenerative disorder, including a diagnosis of mild cognitive impairment or dementia 7. History of significant head trauma or recurrent concussions requiring hospitalization followed by persistent neurologic defaults or known structural brain abnormalities 8. Pain or sleep disorder that could interfere with cognitive testing 9. Major medical concerns that might interfere with cognitive testing 10. Recent history of substance/drug abuse 11. Known nickel allergy 12. Known cardiac implantable device 13. Known arrhythmias 14. Outside the included age range 15. Pregnant or breast feeding 16. Otherwise unable to use the ANNE sensors; for example, finger amputations.
Contact & Investigator
Jennifer Rabin, PhD
PRINCIPAL INVESTIGATOR
Sunnybrook Research Institute
Frequently Asked Questions
Who can join the NCT06423118 clinical trial?
This trial is open to participants of all sexes, aged 55 Years or older, up to 85 Years, studying Sleep. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06423118 currently recruiting?
Yes, NCT06423118 is actively recruiting participants. Contact the research team at alexander.nyman@sri.utoronto.ca for enrollment information.
Where is the NCT06423118 trial being conducted?
This trial is being conducted at Toronto, Canada.
Who is sponsoring the NCT06423118 clinical trial?
NCT06423118 is sponsored by Sunnybrook Health Sciences Centre. The principal investigator is Jennifer Rabin, PhD at Sunnybrook Research Institute. The trial plans to enroll 300 participants.