Single Dose Escalation Study of CM383 in Healthy Volunteers
Trial Parameters
Brief Summary
This study is a single center, randomized, double-blind, placebo-controlled Phase I clinical study in a single dose escalation to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of CM383 in male healthy subjects.
Eligibility Criteria
Inclusion Criteria: * Healthy males, voluntarily participate; * 18 and 80 years old (including boundary values); * able to communicate well with the researchers and follow up the protocol requirements. Exclusion Criteria: * The average daily smoking volume within three months before screening is greater than 5 cigarettes; * Excessive alcohol consumption within three months before screening, or positive alcohol breath test; * Urine drug abuse screening is positive; * Having a family planning or sperm donation plan; Disagree to adopt efficient contraceptive measures.