| NCT ID | NCT07912307 |
| Status | Recruiting |
| Phase | — |
| Sponsor | McMaster University |
| Condition | Exercise |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2026-11 |
| Primary Completion | 2027-02 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2026-11 with a primary completion date of 2027-02.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A single bout of exercise can improve cognitive abilities like memory and attention. These functions help us navigate through everyday life. However, we do not fully understand how exercise improves cognitive abilities. We believe that exercise improves the brain by increasing the amount of BDNF in the blood. BDNF is very important for learning and memory. However, we still do not know if BDNF responds differently to exercise between females and males. The purpose of this work is to characterize potential sex-differences in the circulating BDNF response to acute exercise. We will test the hypothesis that males will have greater serum and plasma BDNF responses compared to females following a maximal exercise test.
Eligibility Criteria
Inclusion Criteria: * Between the ages of 18 and 35 Exclusion Criteria: * presence of type 2 diabetes * history of hypoglycaemia * history of concussion(s) with persistent symptoms * presence of major depressive disorder * history of cardiovascular events requiring hospitalization (i.e., heart attack, stroke) * presence of respiratory disease (e.g. asthma) * pre-existing injuries that prevent aerobic exercise participation.
Contact & Investigator
Jeremy J Walsh, PhD
PRINCIPAL INVESTIGATOR
McMaster University
Frequently Asked Questions
Who can join the NCT07912307 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 35 Years, studying Exercise. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07912307 currently recruiting?
Yes, NCT07912307 is actively recruiting participants. Contact the research team at walshj18@mcmaster.ca for enrollment information.
Where is the NCT07912307 trial being conducted?
This trial is being conducted at Hamilton, Canada.
Who is sponsoring the NCT07912307 clinical trial?
NCT07912307 is sponsored by McMaster University. The principal investigator is Jeremy J Walsh, PhD at McMaster University. The trial plans to enroll 50 participants.