NCT05381792 Serial Gut Microbiome and Bacterial Gene Markers Changes After Endoscopic Resection of Colorectal Advanced Neoplasia
| NCT ID | NCT05381792 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | Colorectal Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2022-09-01 |
| Primary Completion | 2024-12-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2022-09-01 with a primary completion date of 2024-12-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators hypothesize that gut microbiome composition and the four bacterial gene markers (M3) show dynamic changes after endoscopic resection of advanced neoplasia, some key bacteria are associated with restoration of gut microbiome after endoscopic resection.
Eligibility Criteria
Inclusion Criteria: * Subjects require endoscopic resection (e.g. endoscopic mucosal resection or endoscopic submucosal dissection) for advanced adenoma or early-stage colorectal cancer; * Aged 18-90 years old; * Written informed consent obtained. Exclusion Criteria: * Absolute contraindications to colonoscopy (e.g. perforation, intestinal obstruction, unstable cardiopulmonary status); * Contraindications to endoscopic resection (e.g. active gastrointestinal bleeding, uninterrupted anticoagulation or dual antiplatelets); * Known pregnancy or lactation; * Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above);
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05381792 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05381792 currently recruiting?
Yes, NCT05381792 is actively recruiting participants. Contact the research team at mindai@link.cuhk.edu.hk for enrollment information.
Where is the NCT05381792 trial being conducted?
This trial is being conducted at Shatin, Hong Kong.
Who is sponsoring the NCT05381792 clinical trial?
NCT05381792 is sponsored by Chinese University of Hong Kong. The trial plans to enroll 50 participants.
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