Recruiting NCT05774561

Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring

Trial Parameters

Condition Cervical Cancer

Sponsor The Institute of Molecular and Translational Medicine, Czech Republic

Study Type OBSERVATIONAL

Phase N/A

Enrollment 480

Sex ALL

Min Age 18 Years

Max Age 99 Years

Start Date 2022-06-01

Completion 2026-05-31

All Conditions

Cervical Cancer Cervical Dysplasia Oropharyngeal Cancer Human Papillomavirus Infection

Interventions

Arm A - Diagnostic test: HPV detection in liquid biopsiesArm B - Diagnostic test: HPV detection in liquid biopsies

Brief Summary

This trial will evaluate the possible benefits and the performance of liquid biopsies in HPV-associated cancer treatment monitoring. This study aims to find a combination of an adequately sensitive and specific sampling method and biomarkers for early risk stratification of disease recurrence.

Eligibility Criteria

Inclusion Criteria: Women diagnosed with CC/HSIL. Men and women diagnosed with OPC. Patients must agree with study enrollment and must sign study informed consent. Exclusion Criteria: No exclusion criteria are set.

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