NCT07387432 Role of Exercise in PRISm and Subsequent Development of COPD
| NCT ID | NCT07387432 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Hong Kong |
| Condition | Preserved Ratio Impaired Spirometry (PRISM) |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2025-07-14 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2025-07-14 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted. While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.
Eligibility Criteria
Inclusion Criteria: * Age 18 or above * Smoker/ ex-smoker * Spirometry shows PRISm, with FEV1/FVC \>= 0.7 and FEV1 \<80% predicted * Ambulatory to walk * Able to give informed consent Exclusion Criteria: * Age below 18 * Non-smoker * Spirometry does not show PRISm/ unable to perform spirometry * Requires assistance for walking * Unable to give informed consent
Contact & Investigator
King Pui Florence Chan, MD
PRINCIPAL INVESTIGATOR
he University of Hong Kong, Queen Mary Hospital
Frequently Asked Questions
Who can join the NCT07387432 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Preserved Ratio Impaired Spirometry (PRISM). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07387432 currently recruiting?
Yes, NCT07387432 is actively recruiting participants. Contact the research team at kpfchan@hku.hk for enrollment information.
Where is the NCT07387432 trial being conducted?
This trial is being conducted at Hong Kong, China.
Who is sponsoring the NCT07387432 clinical trial?
NCT07387432 is sponsored by The University of Hong Kong. The principal investigator is King Pui Florence Chan, MD at he University of Hong Kong, Queen Mary Hospital. The trial plans to enroll 90 participants.