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Recruiting NCT04578171

NCT04578171 Residual Exacerbations With Mepolizumab

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Clinical Trial Summary
NCT ID NCT04578171
Status Recruiting
Phase
Sponsor Laval University
Condition Asthma
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2021-07-06
Primary Completion 2027-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 90 Years
Study Type OBSERVATIONAL
Interventions
Mepolizumab

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2021-07-06 with a primary completion date of 2027-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This will be a two-year prospective study to characterize the nature of the remaining asthma exacerbations in patients treated with mepolizumab. Participants will be assessed every six months from pre- until two years of treatment in addition to whenever they experience an exacerbation of asthma during the study period. During these visits, various clinical, physiological and inflammatory outcomes will be assessed.

Eligibility Criteria

Inclusion Criteria: * With a proven diagnosis of severe asthma as defined by the Canadian Thoracic Society * Eligible for mepolizumab treatment * Able and willing to sign the informed consent form Exclusion Criteria: * Any respiratory disease apart from asthma * Confounding comorbidities sur as eosinophilic granulomatosis with polyangiitis (EGPA) or hypereosinophilic syndrome

Contact & Investigator

Central Contact

Marie-Eve Boulay, MSc

✉ marie-eve.boulay@criucpq.ulaval.ca

📞 4186568711

Principal Investigator

Andréanne Côté, MD

PRINCIPAL INVESTIGATOR

IUCPQ-UL

Frequently Asked Questions

Who can join the NCT04578171 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Asthma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04578171 currently recruiting?

Yes, NCT04578171 is actively recruiting participants. Contact the research team at marie-eve.boulay@criucpq.ulaval.ca for enrollment information.

Where is the NCT04578171 trial being conducted?

This trial is being conducted at Québec, Canada.

Who is sponsoring the NCT04578171 clinical trial?

NCT04578171 is sponsored by Laval University. The principal investigator is Andréanne Côté, MD at IUCPQ-UL. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology