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Recruiting NCT07198568

Relationship Between Swallowing Dynamics and Suprahyoid Muscle Activity in Sarcopenic Dysphagia

Trial Parameters

Condition Sarcopenia in Elderly
Sponsor Inha University Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 50
Sex ALL
Min Age 65 Years
Max Age N/A
Start Date 2024-06-03
Completion 2026-03
Interventions
Surface electromyographyVideofluoroscopic swallowing study (VFSS)

Brief Summary

Sarcopenic dysphagia is defined as swallowing difficulty among the elderly due to the loss of whole body skeletal and swallowing muscle mass and function. However, the pathophysiology and dynamics of swallowing in sarcopenic dysphagia have been poorly investigated. Therefore, the present study aims to investigate the characteristics of sarcopenic dysphagia using the Videofluoroscopic study (VFSS) focusing on each phase of dysphagia, and surface Electromyography (surface EMG) to assess suprahyoid muscle activity. In sarcopenic dysphagia, impairments will occur in both the oral and pharyngeal phases, particularly affecting bolus formation, premature bolus spillage and laryngeal elevation during swallowing due to the loss of swallowing muscle mass and function. These changes will be considered to have led to an change of duration and amplitude of suprahyoid muscle activity measured via surface EMG.

Eligibility Criteria

Inclusion Criteria: * 65 years of age or older who underwent VFSS to evaluate the presence of dysphagia * Patient who diagnosed with sarcopenia based on the cutoff values of the Asian Working Group for Sarcopenia (AWGS) 2019 * Cognitive ability to follow instructions for Videofluoroscopic swallowing study, surface electromyography. Exclusion Criteria: * History of cerebral hemorrhage or cerebral infarction * History of neuromuscular diseases that could lead to dysphagia such as Parkinson's disease, amyotrophic lateral sclerosis, Guillain-Barre disease * History of Tracheostomy * History of oropharyngeal cancer * History of esophageal structural disease that could lead to dysphagia * History of connective tissue disease * History of cervical surgical procedure * Cognitive impairment who cannot follow instructions for Videofluoroscopic swallowing study, surface electromyography

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