NCT04754854 Reduction of Blood Recirculation in Veno-Venous ECMO
| NCT ID | NCT04754854 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Charite University, Berlin, Germany |
| Condition | Extracorporeal Membrane Oxygenation |
| Study Type | OBSERVATIONAL |
| Enrollment | 136 participants |
| Start Date | 2020-11-20 |
| Primary Completion | 2026-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 136 participants in total. It began in 2020-11-20 with a primary completion date of 2026-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Blood which recirculates through the circuit of a veno-venous Extracorporeal Membrane Oxygenation (V-V ECMO) does not contribute to the systemic oxygenation of a patient on V-V ECMO and is called the recirculation fraction (Rf). Theoretically, the optimization of ECMO blood flow is possible using Rf measurements. A prospective, observational study will be performed measuring the Rf of total ECMO blood flow in patients with acute respiratory distress syndrome (ARDS) on V-V ECMO with an ultrasound dilution technique. ECMO blood flow will be optimized by reducing ECMO blood flow in accordance with the measured Rf as long as systemic oxygenation is not compromised.
Eligibility Criteria
Patients aged 18 years or older requiring veno-venous ECMO for treatment of refractory hypoxemia in ARDS.
Contact & Investigator
Martin Russ, Dr. med.
PRINCIPAL INVESTIGATOR
Charite University Hospital Berlin
Frequently Asked Questions
Who can join the NCT04754854 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Extracorporeal Membrane Oxygenation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04754854 currently recruiting?
Yes, NCT04754854 is actively recruiting participants. Contact the research team at steffen.weber-carstens@charite.de for enrollment information.
Where is the NCT04754854 trial being conducted?
This trial is being conducted at Berlin, Germany.
Who is sponsoring the NCT04754854 clinical trial?
NCT04754854 is sponsored by Charite University, Berlin, Germany. The principal investigator is Martin Russ, Dr. med. at Charite University Hospital Berlin. The trial plans to enroll 136 participants.