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Recruiting NCT03299608

Rapid Analysis of Infections by Spectrometry of Exhaled Breath

Trial Parameters

Condition Respiratory Tract Infections
Sponsor Universitaire Ziekenhuizen KU Leuven
Study Type OBSERVATIONAL
Phase N/A
Enrollment 246
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2019-06-21
Completion 2025-06
Interventions
Breath analysis

Brief Summary

To quantify the diagnostic, prognostic and therapeutic value of spectrometric analysis of exhaled breath from hematological patients with respiratory infection.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18y at start of study * One of the following diagnoses: * De novo, refractory or relapsed AML/MDS receiving intensive chemotherapy * De novo, refractory or relapsed ALL/T-lymphoblastic lymphoma receiving intensive chemotherapy * Aplastic anemia requiring ATG therapy * Any patient admitted for either autologous hematopoietic stem cell transplantation. Transplantation may not have been performed at time of enrolment. * Any patient admitted with allogeneic hematopoietic stem cell transplantation within the last year, or planned during this admission. * Written informed consent obtained from the patient Exclusion Criteria: * Hematological disease beyond the specified inclusion criteria * Signs of active respiratory infection * If previously enrolled: incomplete clearance of all signs of respiratory infection (both clinically, microbiologically and radiologically).

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