NCT04580225 Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE)
| NCT ID | NCT04580225 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alberta |
| Condition | Wrist Arthritis |
| Study Type | INTERVENTIONAL |
| Enrollment | 170 participants |
| Start Date | 2021-01-07 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 170 participants in total. It began in 2021-01-07 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized clinical trial (RCT) aims to compare clinical and radiographic outcomes of different partial wrist fusion techniques in participants with post-traumatic wrist arthritis. Participants with stage II or III scapholunate advanced collapse (SLAC) or scaphoid nonunion advanced collapse (SNAC) who meet the eligibility criteria will be randomly assigned to one of two parallel groups: Group A (partial wrist arthrodesis without triquetral excision i.e. four-corner arthrodesis), or Group B (partial wrist arthrodesis with triquetral excision i.e. three-corner or capitolunate arthrodesis with triquetral excision). The results of this study will provide evidence to guide surgeons in determining the ideal wrist fusion technique in the management of patients with post-traumatic wrist arthritis requiring surgery.
Eligibility Criteria
Inclusion Criteria: * Participant has a stage II or III scapholunate advanced collapse (SLAC) or scaphoid nonunion advanced collapse (SNAC) wrist and is a surgical candidate for the included surgical interventions Exclusion Criteria: * Participant has been diagnosed with other forms of wrist arthritis other than SLAC or SNAC * Participant has significant arthritis of the ipsilateral hand/finger joint(s), major joint trauma, previous major wrist surgery, infection or neuromuscular pathology affecting the function of the ipsilateral upper extremity or ability to make a fist * Participant has a physical or mental health condition preventing completion of consent or questionnaires * Participant does not speak/read/understand English * Participant has no fixed address or means of contact * Participant is unwilling to complete necessary follow-ups * Surgeon concludes that eligible salvage techniques are not appropriate at the time of surgery (based on injury characteristics or concomitant wrist pathology)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04580225 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Wrist Arthritis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04580225 currently recruiting?
Yes, NCT04580225 is actively recruiting participants. Contact the research team at badre@ualberta.ca for enrollment information.
Where is the NCT04580225 trial being conducted?
This trial is being conducted at Calgary, Canada, Calgary, Canada, St. Albert, Canada, London, Canada and 2 additional locations.
Who is sponsoring the NCT04580225 clinical trial?
NCT04580225 is sponsored by University of Alberta. The trial plans to enroll 170 participants.