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Recruiting Phase 2 NCT07751159

NCT07751159 Radiation Therapy Approaches for People With Prostate Cancer

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Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT07751159
Status Recruiting
Phase Phase 2
Sponsor Memorial Sloan Kettering Cancer Center
Condition Prostate Cancer Patients
Study Type INTERVENTIONAL
Enrollment 126 participants
Start Date 2026-07-31
Primary Completion 2030-07-31

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Standard of Care HDR BrachytherapySBRT

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 126 participants in total. It began in 2026-07-31 with a primary completion date of 2030-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of the study is to explore the best ways of giving radiation therapy to balance cancer control and treatment side effects.

Eligibility Criteria

Inclusion Criteria: * Non-metastatic prostate cancer. * Classified as unfavorable intermediate-, high-, or very high-risk prostate cancer according to NCCN risk stratification guidelines. (Note: cT3a or T3b by MRI or PSMA PET allowed) * Considered by the treating radiation oncologist as a suitable candidate for both HDR brachytherapy boost and SBRT Exclusion Criteria: * None

Contact & Investigator

Central Contact

Daniel Gorovets, MD

✉ gorovetd@mskcc.org

📞 212-639-3983

Principal Investigator

Daniel Gorovets, MD

PRINCIPAL INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Frequently Asked Questions

Who can join the NCT07751159 clinical trial?

This trial is open to participants of all sexes, studying Prostate Cancer Patients. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07751159 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07751159 currently recruiting?

Yes, NCT07751159 is actively recruiting participants. Contact the research team at gorovetd@mskcc.org for enrollment information.

Where is the NCT07751159 trial being conducted?

This trial is being conducted at Basking Ridge, United States, Middletown, United States, Montvale, United States, Commack, United States and 3 additional locations.

Who is sponsoring the NCT07751159 clinical trial?

NCT07751159 is sponsored by Memorial Sloan Kettering Cancer Center. The principal investigator is Daniel Gorovets, MD at Memorial Sloan Kettering Cancer Center. The trial plans to enroll 126 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology