NCT07516652 Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release
| NCT ID | NCT07516652 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Washington University School of Medicine |
| Condition | Trigger Finger |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2026-04-01 |
| Primary Completion | 2027-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2026-04-01 with a primary completion date of 2027-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to compare two different skin incisions used in surgery to treat trigger finger in adult patients. Trigger finger occurs when a finger gets stuck or locks because of swelling of the sheath around the tendons the help move the fingers. The main questions it aims to answer are (1) Does the type of skin cut affect how well the hand works 6 weeks after surgery? (2) Does the type of skin cut affect pain levels, scar healing, and how quickly people return to their normal activities? Orthopaedic surgeons will compare a straight incision along the finger (longitudinal incision) to a incision across the crease in the palm (transverse incision) to see if one type of incision results in better recovery, less pain, a better scar, and higher patient satisfaction with the procedure. Participants who have trigger finger and are indicated for surgery will have surgery to release the pulley in their finger using one of the two types of incisions (assigned by chance). Participants will fill out questionnaires about their hand function and pain before surgery and at follow-up visits. Participants will have their scar checked and rated at about 2, 6, and 12 weeks after surgery, and report on their pain for the first few days after surgery and when they can return to work and move their finger without pain.
Eligibility Criteria
Inclusion Criteria: * Adult patients (age ≥ 18 years) * Diagnosed with trigger finger (stenosing tenosynovitis) of a finger (excluding the thumb) * Written informed consent obtained Exclusion Criteria: * Revision surgery * Previous surgery on the affected finger * Patients refusing consent
Contact & Investigator
Jason Strelzow, MD
PRINCIPAL INVESTIGATOR
Associate Professor, Orthopaedic Surgery Division of Hand and Microsurgery, Washington University in St Louis
Frequently Asked Questions
Who can join the NCT07516652 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Trigger Finger. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07516652 currently recruiting?
Yes, NCT07516652 is actively recruiting participants. Contact the research team at kale.n@wustl.edu for enrollment information.
Where is the NCT07516652 trial being conducted?
This trial is being conducted at Chicago, United States, St Louis, United States.
Who is sponsoring the NCT07516652 clinical trial?
NCT07516652 is sponsored by Washington University School of Medicine. The principal investigator is Jason Strelzow, MD at Associate Professor, Orthopaedic Surgery Division of Hand and Microsurgery, Washington University in St Louis. The trial plans to enroll 200 participants.