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Recruiting NCT02417714

NCT02417714 Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

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Clinical Trial Summary
NCT ID NCT02417714
Status Recruiting
Phase
Sponsor National Heart, Lung, and Blood Institute (NHLBI)
Condition Healthy Subjects
Study Type OBSERVATIONAL
Enrollment 215 participants
Start Date 2014-09-08
Primary Completion 2026-09-22

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 99 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 215 participants in total. It began in 2014-09-08 with a primary completion date of 2026-09-22.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Background: \- Computed Tomography (CT) is a scan that makes detailed pictures of the body. It uses radiation to do that. In 2011, about 85.3 million CT scans were done in the United States. But there is growing concern about the health effects of radiation. There are new and different ways to make CT pictures that use less radiation. Researchers want to learn whether these new methods create images that are similar to images from a traditional CT. Objective: \- To learn if new CT imaging methods with less radiation make images that are similar to traditional ways. Eligibility: \- Adults 18 years of age and older who are scheduled for a CT of the chest, abdomen and pelvis with contrast. Design: * Researchers will review participants medical records to see if they can be in this study. * Participants may have blood drawn from an arm vein by a needle stick. The blood will be used to make sure they can be in this study and that it is safe for them to have contrast. * During the participants CT scan appointment, one extra scan will be done using low radiation methods. * During a CT scan, the participant lies on a table. A large x-ray machine takes pictures of the body.

Eligibility Criteria

* INCLUSION CRITERIA: Inclusion Criteria for Body CT: 1. Clinical indication for a chest, abdomen and pelvis CT with contrast 2. Age equal to or greater than 18 years 3. Able to understand and willing to sign the Informed Consent Form Inclusion Criteria for Chest CT: 1. Clinical indication for a CT with or without contrast that includes the chest 2. Age equal to or greater than 18 years 3. Able to understand and willing to sign the Informed Consent Form EXCLUSION CRITERIA: Exclusion Criteria for Body CT: 1. Pregnancy 2. Serum Cr \> 1.5 mg/dL 3. Clinical CT scan with more than one contrast imaging phase (for example three phase liver) Exclusion Criteria for Chest CT 1\. Pregnancy

Contact & Investigator

Central Contact

Margaret C Lowery, R.N.

✉ peg.lowery@nih.gov

📞 (301) 451-3128

Principal Investigator

Marcus Y Chen, M.D.

PRINCIPAL INVESTIGATOR

National Heart, Lung, and Blood Institute (NHLBI)

Frequently Asked Questions

Who can join the NCT02417714 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Healthy Subjects. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT02417714 currently recruiting?

Yes, NCT02417714 is actively recruiting participants. Contact the research team at peg.lowery@nih.gov for enrollment information.

Where is the NCT02417714 trial being conducted?

This trial is being conducted at Bethesda, United States.

Who is sponsoring the NCT02417714 clinical trial?

NCT02417714 is sponsored by National Heart, Lung, and Blood Institute (NHLBI). The principal investigator is Marcus Y Chen, M.D. at National Heart, Lung, and Blood Institute (NHLBI). The trial plans to enroll 215 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology