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Recruiting NCT06179602

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors

Trial Parameters

Condition Liver Cancer
Sponsor Leiden University Medical Center
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,500
Sex ALL
Min Age 18 Years
Max Age 110 Years
Start Date 2024-01-01
Completion 2027-12-15

Brief Summary

The endpoint of this study is to develop and validate algorithms, using artificial intelligence and machine learning, to optimize patient selection, treatment planning, treatment evaluation and outcome prediction in patients undergoing thermal ablation of a malignant liver tumor. The long-term objective is to establish thermal ablation as the treatment of choice for the vast majority of patients with a primary or secondary liver tumor by development of an accessible workflow that can be widely implemented in different centers performing thermal ablation. Over a time span of at least four years, data will be collected prospectively, encompassing patient information, tumor characteristics, and treatment details. Additionally, pre-, intra-, and post-procedural imaging will be systematically gathered.

Eligibility Criteria

Inclusion Criteria: * 18 years or above * Candidate for percutaneous thermal liver ablation as discussed in a multidisciplinary tumorboard (MDT) * Informed consent Exclusion Criteria: * Patients lacking capacity to give informed consent.

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