Trial Parameters
Brief Summary
The primary objective of this observational registry is to develop a comprehensive clinical and imaging score (incorporating echocardiography and cardiac magnetic resonance data) that enhances risk stratification for patients with Takotsubo syndrome. The secondary objectives of this registry are as follows: Investigate the diagnostic value of cardiac magnetic resonance parameters in predicting in-hospital and long-term outcomes in patients with Takotsubo syndrome. Compare the proposed risk stratification score for patients with Takotsubo syndrome with previously existing scores. Investigate the contribution of machine learning models in predicting in-hospital and long-term outcomes compared to standard clinical scores. The design and rationale of this registry are available at 10.1097/RTI.0000000000000709
Eligibility Criteria
Inclusion Criteria: * Takotsubo syndrome diagnosis (according to Position Statement of the European Society of Cardiology Heart Failure Association) * Adult patients ( \> 18y old) * Availability at baseline of clinical variables, standard transthoracic echocardiography, and cardiovascular magnetic resonance acquisition Exclusion Criteria: * \<18 y old * Lack of transthoracic echocardiography and cardiovascular magnetic resonance examinations * Preexisting cardiomyopathies * Previous myocardial infarction * Suspected or known prior irreversible myocardial damage * Valvular heart disease