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Recruiting NCT06423508

NCT06423508 PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals

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Clinical Trial Summary
NCT ID NCT06423508
Status Recruiting
Phase
Sponsor University of Vienna
Condition Gut Microbiome
Study Type OBSERVATIONAL
Enrollment 52 participants
Start Date 2024-12-03
Primary Completion 2024-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 52 participants in total. It began in 2024-12-03 with a primary completion date of 2024-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study aims to assess the effectiveness of various commercial and non-hazardous buffers for the storage of human gut fecal samples over time. This evaluation will be conducted by comparing the performance of these buffers against directly frozen samples using metaproteomic analysis. The study is motivated by the need for standardized protocols for sample preservation in metaproteomic research, particularly focusing on protein preservation in fecal samples. By investigating proteomic, taxonomic, and functional identifications, the research seeks to provide insights into the reliability of these buffers as storage solutions. Additionally, the study plans to explore inter- and intra-individual variabilities at the proteome level by periodically collecting fecal samples from volunteers, complementing existing knowledge in metaproteomics. Overall, the study addresses a critical gap in the field and has the potential to enhance reproducibility and comparability across metaproteomic studies

Eligibility Criteria

Inclusion Criteria: * agreeing to participate after signing the informed consent form and * being 18-70 years old. Exclusion Criteria: * take antibiotics during the previous 1 month * had undergone gastrointestinal surgery

Contact & Investigator

Central Contact

David Gomez Varela PhD. Senior Scientist, PhD

✉ david.gomez.varela@univie.ac.at

📞 1427755361

Principal Investigator

Giacomo Carta, PhD

PRINCIPAL INVESTIGATOR

University of Vienna

Frequently Asked Questions

Who can join the NCT06423508 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Gut Microbiome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06423508 currently recruiting?

Yes, NCT06423508 is actively recruiting participants. Contact the research team at david.gomez.varela@univie.ac.at for enrollment information.

Where is the NCT06423508 trial being conducted?

This trial is being conducted at Vienna, Austria.

Who is sponsoring the NCT06423508 clinical trial?

NCT06423508 is sponsored by University of Vienna. The principal investigator is Giacomo Carta, PhD at University of Vienna. The trial plans to enroll 52 participants.

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