← Back to Clinical Trials
Recruiting NCT05432297

NCT05432297 Preventive Physical Activity Intervention in Head and Neck Cancer

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05432297
Status Recruiting
Phase
Sponsor Sahlgrenska University Hospital
Condition Head and Neck Neoplasms
Study Type INTERVENTIONAL
Enrollment 80 participants
Start Date 2023-01-02
Primary Completion 2027-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Preventive physical exercise

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 80 participants in total. It began in 2023-01-02 with a primary completion date of 2027-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study includes patients with tumors of the oropharynx, larynx and hypopharynx scheduled to receive radiotherapy with curative intent (+/- chemotherapy). The patients will be randomized into either an intervention group (performing a preventive physical activity protocol before and during radiotherapy) or a control group not performing a specified physical exercise protocol. All patients will be in contact with with a speech language pathologist or a physical therapist weekly during radiotherapy. The study is expected to improve physical function and quality of life during and after oncologic treatment

Eligibility Criteria

Inclusion Criteria: * Head and neck cancer (tumors of the oropharynx, pharynx, hypopharynx and larynx) * Receiving radiohterapy (+/- chemotherapy) with curative intent Exclusion Criteria: * Surgery due to head and neck cancer * Previous treatment for head and neck cancer * Tracheostomized patients * Inability to perform exercise intervention * Inability to perform part of 6-minute walking test * Inability to independently fill out questionnaires in Swedish * Previous neurologic or neuromuscular disease

Contact & Investigator

Central Contact

Lisa Tuomi, PhD

✉ tuomi.lisa@gu.se

📞 +46313421000

Principal Investigator

Lisa Tuomi, PhD

PRINCIPAL INVESTIGATOR

Sahlgrenska University Hospital

Frequently Asked Questions

Who can join the NCT05432297 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Head and Neck Neoplasms. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05432297 currently recruiting?

Yes, NCT05432297 is actively recruiting participants. Contact the research team at tuomi.lisa@gu.se for enrollment information.

Where is the NCT05432297 trial being conducted?

This trial is being conducted at Gothenburg, Sweden.

Who is sponsoring the NCT05432297 clinical trial?

NCT05432297 is sponsored by Sahlgrenska University Hospital. The principal investigator is Lisa Tuomi, PhD at Sahlgrenska University Hospital. The trial plans to enroll 80 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology