Prehabilitation for Patients Awaiting Liver Transplantation
Trial Parameters
Brief Summary
This study will assess the feasibility, safety and effectiveness of a structured prehabilitation program combining exercise training, nutritional optimization and psychological support for patients with cirrhosis awaiting liver transplantation.
Eligibility Criteria
Inclusion Criteria: * Age above 18 years * Diagnosis of cirrhosis, based on a combination of clinical, laboratory, imaging, or histology * Active on the liver transplant waiting list of the MUHC Exclusion Criteria: * Biological Model for End Stage Liver Disease \>20 * Hepatic decompensation within the last month * High risk varices not on primary or secondary prevention * Recurrent large volume paracentesis * Persistent hepatic encephalopathy * Platelets \<20,000/µL, or hemoglobin \<80g/L * Altered hemodynamics * Significant heart disease * Awaiting combined organ transplantation * Awaiting repeat liver transplantation * Condition limiting mobilization and/or exercise, or recurrent falls