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Recruiting NCT06716463

NCT06716463 PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study

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Clinical Trial Summary
NCT ID NCT06716463
Status Recruiting
Phase
Sponsor Unity Health Toronto
Condition Ventilatory Failure
Study Type OBSERVATIONAL
Enrollment 80 participants
Start Date 2025-01-27
Primary Completion 2025-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 80 participants in total. It began in 2025-01-27 with a primary completion date of 2025-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to assess the potential non-invasive tools (e.g. regional ventilation, respiratory muscle response, lung mechanic's parameters) to identify the risk of failure when using high flow nasal cannula (HFNC) or non-invasive ventilation (NIV). The main question, it aims to answer is: Does abnormal regional ventilation could predict HFNC or NIV failure?

Eligibility Criteria

Inclusion Criteria: * Age of ≥ 18 years * Using NIV or HFNC anywhere in the hospital Exclusion Criteria: * Chronic CO2 retention * Neuromuscular disorder * Requiring home NIV (CPAP or BIPAP) * Tracheostomy * Contraindication to EIT placement: pacemaker/defibrillator implantation, burns at the area of EIT placement

Frequently Asked Questions

Who can join the NCT06716463 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Ventilatory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06716463 currently recruiting?

Yes, NCT06716463 is actively recruiting participants. Visit ClinicalTrials.gov or contact Unity Health Toronto to inquire about joining.

Where is the NCT06716463 trial being conducted?

This trial is being conducted at Toronto, Canada.

Who is sponsoring the NCT06716463 clinical trial?

NCT06716463 is sponsored by Unity Health Toronto. The trial plans to enroll 80 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology