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Recruiting NCT05876130

Postoperative Hypofractionated Intensity-modulated Radiotherapy Endometrial Cancer

Trial Parameters

Condition Endometrial Cancer
Sponsor Samsung Medical Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 92
Sex FEMALE
Min Age 20 Years
Max Age 80 Years
Start Date 2022-11-01
Completion 2031-12-31
Interventions
POHIM_EM

Brief Summary

To investigate the non-inferiority of disease-free survival in women who received hypofractionated intensity-modulated whole pelvic radiation therapy (2.5 Gy x 16 fractions) after curative surgery for stage III endometrial cancer.

Eligibility Criteria

Inclusion Criteria: * histologically confirmed endometrioid type endometrial cancer * completion of hysterectomy and surgical staging * pathologically confirmed FIGO stage III * ECOG performance status 0 or 1 * adjuvant chemotherapy was done or planned Exclusion Criteria: * presence of distant metastasis * previous history of pelvic radiotherapy * severe and unstable medical condition * previous history of other carcinoma except for thyroid cancer, skin cancer, and endometrial cancer

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