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Recruiting Phase 3 NCT06056830

NCT06056830 Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

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Clinical Trial Summary
NCT ID NCT06056830
Status Recruiting
Phase Phase 3
Sponsor Clarity Pharmaceuticals Ltd
Condition Prostate Cancer
Study Type INTERVENTIONAL
Enrollment 383 participants
Start Date 2023-12-21
Primary Completion 2026-09

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
64Cu-SAR-bisPSMA

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.

This trial targets 383 participants in total. It began in 2023-12-21 with a primary completion date of 2026-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim for this study is to assess the diagnostic performance of 64Cu-SAR-bisPSMA PET to detect regional nodal metastases.

Eligibility Criteria

Inclusion Criteria: * At least 18 years of age. * Signed informed consent. * Untreated, histologically confirmed adenocarcinoma of the prostate. * High-risk or greater PC defined by National Comprehensive Cancer Network Guidelines Version 1.202327 (clinical stage ≥T3a, or Grade Group ≥4, or PSA \>20 ng/mL). * Patients electing to undergo RP with PLND. Exclusion Criteria: * Administration of any high energy (\>300 KeV) gamma-emitting radioisotope within 5 physical half-lives prior to Day 1. * Known or expected hypersensitivity to 64Cu-SAR-bisPSMA or any of its components. * Patients with known predominant small cell or neuroendocrine PC.

Contact & Investigator

Central Contact

Clarity Pharmaceuticals

✉ clinicaltrials@claritypharmaceuticals.com

📞 +61 (0) 2 9209 4037

Principal Investigator

Clarity Pharmaceuticals

STUDY DIRECTOR

Clarity Pharmaceuticals

Frequently Asked Questions

Who can join the NCT06056830 clinical trial?

This trial is open to male participants only, aged 18 Years or older, studying Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06056830 trial and what does that mean for participants?

Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 383 participants.

Is NCT06056830 currently recruiting?

Yes, NCT06056830 is actively recruiting participants. Contact the research team at clinicaltrials@claritypharmaceuticals.com for enrollment information.

Where is the NCT06056830 trial being conducted?

This trial is being conducted at Birmingham, United States, Phoenix, United States, Little Rock, United States, Los Angeles, United States and 11 additional locations.

Who is sponsoring the NCT06056830 clinical trial?

NCT06056830 is sponsored by Clarity Pharmaceuticals Ltd. The principal investigator is Clarity Pharmaceuticals at Clarity Pharmaceuticals. The trial plans to enroll 383 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology