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Recruiting NCT06667427

NCT06667427 Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

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Clinical Trial Summary
NCT ID NCT06667427
Status Recruiting
Phase
Sponsor M.D. Anderson Cancer Center
Condition Cancer
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-01-13
Primary Completion 2026-08-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Nerve transfer techniques

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2025-01-13 with a primary completion date of 2026-08-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.

Eligibility Criteria

Inclusion Criteria: In order to be eligible to participate in the intervention group of this study, an individual must meet all of the following criteria: * Provision of signed and dated informed consent form * Aged 18 or greater * Patient scheduled to undergo facial nerve transfer * Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study In order to be eligible to participate in the non-intervention historical control group of this study, an individual must meet all of the following criteria: * Provision of signed and dated informed consent form * Aged 18 or greater * Previous facial surgery severing a facial nerve without graft or other form of dynamic facial nerve reconstruction within the last 20 years Exclusion Criteria: Patients known to be pregnant

Contact & Investigator

Central Contact

Z-Hye Lee, MD

✉ zlee@mdanderson.org

📞 713-563-4598

Principal Investigator

Z-Hye Lee, MD

PRINCIPAL INVESTIGATOR

M.D. Anderson Cancer Center

Frequently Asked Questions

Who can join the NCT06667427 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06667427 currently recruiting?

Yes, NCT06667427 is actively recruiting participants. Contact the research team at zlee@mdanderson.org for enrollment information.

Where is the NCT06667427 trial being conducted?

This trial is being conducted at Houston, United States.

Who is sponsoring the NCT06667427 clinical trial?

NCT06667427 is sponsored by M.D. Anderson Cancer Center. The principal investigator is Z-Hye Lee, MD at M.D. Anderson Cancer Center. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology