NCT05875155 Ovarian Tissue Cryopreservation for Fertility Preservation
| NCT ID | NCT05875155 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pittsburgh |
| Condition | Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2011-01-13 |
| Primary Completion | 2031-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2011-01-13 with a primary completion date of 2031-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide research tissue for the following Specific Aims: 1. To optimize techniques for cryopreservation of ovarian tissues from patients at significant risk for infertility. 2. To investigate factors affecting successful maturation ovarian tissue. Participants will undergo a surgical procedure to remove an ovary (oophorectomy) to preserve their gonadal tissue for fertility preservation.
Eligibility Criteria
Inclusion Criteria: * Be female age less than 40 years old. * Unable or unwilling to make use of oocyte or embryo banking alone. * Be scheduled to undergo surgery, chemotherapy, drug treatment and/or radiation for the treatment or prevention of a medical condition or malignancy with risk of causing permanent and complete loss of subsequent ovarian function. * Or, have a medical condition or malignancy that requires removal of all or part of one or both ovaries. * Or, Have newly diagnosed or recurrent disease. Those who were not enrolled at the time of initial diagnosis (i.e., patients with recurrent disease) are eligible if they have not previously received therapy that is viewed as likely to result in complete and permanent loss of ovarian function. * Have two ovaries if undergoing elective removal of an ovary for fertility preservation only. Exclusion Criteria: * Diagnosed with psychological, psychiatric, or other conditions which prevent giving fully informed consent. * Diagnosed with an underlying medical condition that significantly increases their risk of complications from anesthesia and surgery.
Contact & Investigator
Kyle Orwig, PhD
PRINCIPAL INVESTIGATOR
University of Pittsburgh/ University of Pittsburgh Medical Center
Frequently Asked Questions
Who can join the NCT05875155 clinical trial?
This trial is open to female participants only, up to 39 Years, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05875155 currently recruiting?
Yes, NCT05875155 is actively recruiting participants. Contact the research team at fertilitypreservation@upmc.edu for enrollment information.
Where is the NCT05875155 trial being conducted?
This trial is being conducted at Pittsburgh, United States.
Who is sponsoring the NCT05875155 clinical trial?
NCT05875155 is sponsored by University of Pittsburgh. The principal investigator is Kyle Orwig, PhD at University of Pittsburgh/ University of Pittsburgh Medical Center. The trial plans to enroll 500 participants.
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