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Recruiting Phase 2, Phase 3 NCT07075718

NCT07075718 Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

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Clinical Trial Summary
NCT ID NCT07075718
Status Recruiting
Phase Phase 2, Phase 3
Sponsor Glaukos Corporation
Condition Glaucoma
Study Type INTERVENTIONAL
Enrollment 610 participants
Start Date 2025-06-12
Primary Completion 2028-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Gen 2 Travoprost Intracameral ImplantTimolol eye drops 0.5%Sham Procedure

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 610 participants in total. It began in 2025-06-12 with a primary completion date of 2028-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Eligibility Criteria

Inclusion Criteria: * Diagnosis of open-angle glaucoma or ocular hypertension in the study eye Exclusion Criteria: * Prior incisional glaucoma surgery in the study eye * Prior argon laser trabeculoplasty (ALT) in the study eye * Prior minimally invasive glaucoma (MIGS) surgery in the study eye

Contact & Investigator

Central Contact

Study Director

✉ ClinicalResearch@glaukos.com

📞 949-739-8749

Principal Investigator

Luis G. Vargas, MD

STUDY CHAIR

Glaukos Corporation

Frequently Asked Questions

Who can join the NCT07075718 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Glaucoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07075718 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07075718 currently recruiting?

Yes, NCT07075718 is actively recruiting participants. Contact the research team at ClinicalResearch@glaukos.com for enrollment information.

Where is the NCT07075718 trial being conducted?

This trial is being conducted at Grand Junction, United States, Oklahoma City, United States, El Paso, United States.

Who is sponsoring the NCT07075718 clinical trial?

NCT07075718 is sponsored by Glaukos Corporation. The principal investigator is Luis G. Vargas, MD at Glaukos Corporation. The trial plans to enroll 610 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology